Marini SkinSolutions

Marini SkinSolutions Marini Reboot - Anti-Aging PDRN Face Serum - Supports Visibly Smoother Younger-Looking Skin with Enhanced Resilience

4.5(23)
$160.00

160+ bought in the past month

About this item

  • REBOOT SKIN AT EVERY LEVEL - A next-generation solution with concentrated PDRN for enhanced regeneration and rejuvenation. Support recovery, resilience, and long-term skin health for visibly smoother, younger looking skin.
  • FEATURES - Salmon-derived PDRN is a core regenerative technology with highly purified DNA fragments to support skin health and resilience by providing the body with building blocks beneficial to enhanced recovery and repair.
  • BENEFITS - PDRN & advanced rejuvenation and prejuvenation technologies provide enhanced recovery and repair, wrinkle smoothing benefits & structural support. They support resilience, radiance, hydration & barrier repair to soothe and calm skin.
  • PRO TIP - Combine Reboot with any aesthetic service and add to every skin care regimen for enhanced regenerative support and a more complete longevity and wellness-based solution for skin.
  • DISCOVER THE DIFFERENCE - Marini SkinSolutions delivers proven solutions for top skin concerns for individuals of every age, skin type & tone. Backed by science, our formulations provide effective, research-driven results you can trust.
  • FORMULATED WITH CARE - Every product undergoes rigorous testing to exceed the highest global safety and ingredient standards. To promote transparency, we include a “does not contain” list on each product’s packaging.
$160.00

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Product details
BrandMarini SkinSolutions
Item Volume1 Fluid Ounces
Item dimensions L x W x H1.63 x 1.63 x 4.75 inches
Active IngredientsSalmon Milt Extract (PDRN/Polydeoxyribonucleotide), Rejuvenating Peptides & Structural Support, Palmitoyl Pentapeptide-4, Adenosine, Hydration & Moisture Retention, Sodium Hyaluronate (Hyaluronic Acid), L-Glutamic Acid, Trehalose, Sodium Lactate, Barrier Repair & Skin Protection, Ceramide NP, Squalane, Hydrogenated Olive Oil Unsaponifiables, Pullulan, Soothing, Antioxidant & Microbiome Support, Saccharomyces Lysate Extract, Lactobacillus Ferment Lysate, Curcuma Longa (Turmeric) Root Extract, Panax Ginseng Root Extract, Dioscorea Japonica Root Extract, Arginine See more
Skin TypeNormal
Technical specifications
product_dimensions1.63 x 1.63 x 4.75 inches; 4.48 ounces
upc814924012373
manufacturerMarini SkinSolutions
best_sellers_rank#150,291 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #3,565 in Face Moisturizers

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Customer reviews

4.523 ratings
  1. 567%
  2. 433%
  3. 30%
  4. 20%
  5. 10%
★★★★★

Great Mix of Marini Clinical and K Beauty Actives That Makes My Skin Look Amazing

CustomerMarch 16, 2026

Fewer Fine Lines and Bouncier Skin, Even in the Middle of Winter I got this because it’s one of Marini’s newest anti aging serums, released in early 2026, and the once I saw that it had PDRN and ferments, I knew I wanted it. I’m up for anything that blends Korean style regenerative ingredients with real clinical performance. And since my whole relationship with Jan Marini started years ago when the aesthetician in my dermatologist’s office used her products on me after microneedling and laser, I already trust the brand when it comes to calming my skin and getting my barrier back in shape. So this felt like it was made for me. ➡️ WHAT THE TEXTURE FEELS LIKE ON MY SKIN ➜ The texture is this light gel that absorbs fast, and on my winter dry skin it just disappears in the best way. I get that soft silicone slip at first, and then it settles into a smooth, comfortable finish. The only place I feel a tiny bit of tackiness is my forehead, which always runs a little oilier, but even that goes away once I put moisturizer or sunscreen on. Right now, in the cold, it feels perfect. In the summer, I can already tell it’ll be more of a use when needed serum, but for winter it’s exactly what my skin wants. ➡️ WHY IT WORKS SO WELL WITH MY RETINOL ROUTINE ➜ This serum fits into my retinol routine in a way that feels really natural. Some nights I put it right on top of my encapsulated retinol, and that pairing keeps my skin calm instead of tight or pink. Other nights I skip layering and just use it alone if I want something soothing. And then there are mornings when my skin feels a little overworked, and I use it by itself to settle everything down. ➜ The biggest thing is how "normal but better" my skin feels through the day. Usually, in winter, my skin starts asking for moisture by mid morning, but when I use this at night and again in the morning, that doesn’t happen. My skin stays soft and comfortable, and the pinkness I usually get from retinol is much lower. It makes stronger actives a lot more doable, without the punishment. ➡️ WHY THIS SERUM MATTERS TO ME WITH STRONGER AT HOME ACTIVES AND AT HOME PROCEDURES ➜ This is the part I wish I understood a long time ago. For years I thought I had sensitive skin. Any time I used something strong like retinol, or did dermaplaning, or even just pushed my exfoliation a little too far, my skin would get pink, tight, or just feel off for days. I assumed that meant my skin couldn’t handle these things. ➜ What I eventually learned is that my skin wasn’t the problem. The problem was that I was using all these stronger at home actives and even doing things like dermaplaning or light microneedling, but I wasn’t pairing them with the same level of repair and regeneration that I’d get in a dermatologist’s office. Yes, I know, duh, but whatever, I doubt I'm the only one. Basically, just because I can I do these things at home now doesn’t magically mean my skin needs any less help recovering afterward. ➜ Once I started balancing the strong stuff with equally strong repair, all that sensitive skin I thought I had disappeared. ➜ This serum fills that gap for me. It behaves like the post procedure serums my aesthetician used on me after microneedling and laser. It calms everything down, brings back that soft, hydrated feel, and helps my barrier settle after I’ve done something intense. I wouldn’t use it on day one after microneedling, but on day two and onward it’s perfect for getting my skin back to normal. ➡️ THE INGREDIENTS THAT MAKE THIS FEEL DIFFERENT AND BACK UP WITH CLAIMS ➜ The first thing I noticed on the ingredient list is how high Sodium DNA (PDRN) sits. That’s rare. It means the concentration is actually meaningful, not just a marketing sprinkle. PDRN gives the serum that slightly cushioned feel and a subtle firming effect that I notice the next morning. The ferments give it that Korean recovery vibe I love, and then you have ceramide NP, a peptide, and adenosine rounding everything out. It feels like this perfect blend of Marini’s clinical roots and the Korean ingredients that always work so well for me. ➡️ HOW MY SKIN LOOKS AND FEELS AFTER USING THIS - THE BEST PART! ➜ My skin looks and feels noticeably better when I use this, especially in the anti aging department. I see softer fine lines and a more even tone, and my skin has a firmer, more supported feel that I notice the next morning. The moisture stays steady through the day, which never happens for me in winter. My redness is lower in the morning, and my texture looks smoother. I’ve also noticed fewer fine lines with this treatment. I’m not sure if that’s because this serum is fantastic on its own or because it makes everything else in my routine work better, but the anti aging effects are real for me, especially above and below the corners of my lips. ➡️ THERE IS A LIGHT SCENT BUT IT DOESN'T BOTHER ME AND HOW I USE THIS IN MY ROUTINE IN THE WINTER ➜ There’s a light scent, but it hasn’t irritated my skin at all. I'd prefer there wasn't any scent in here, but that's just my preference. I use this at night over retinol and again in the morning on clean skin, and that routine works really well for me right now. In the warmer months, I’ll probably use it more as a repair serum, especially after dermaplaning or day two microneedling, but for winter it’s one of the few things that keeps my skin comfortable. ➡️ MY OVERALL TAKE ➜ I think this is a standout addition to the Marini line. It’s perfect for people who want high quality skin care and something that actually supports the barrier when you’re using stronger actives or doing at home procedures. And even if you’re not using strong actives at all, it’s still a fantastic serum because of the ingredient quality, how restorative and balanced it feels on the skin, and the real anti aging benefits it gives on its own. It fits right into the clinical world where the brand started, but it also brings in the Korean elements I love, like PDRN and ferments. For my skin, especially in winter, it gives me softness, moisture, a calmer feel, and visible anti aging results. It’s totally worth it. Read more

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★★★★★

Premium PDRN Serum with Advanced Regenerative Ingredients, Priced Accordingly

JeffMarch 2, 2026

Marini SkinSolutions Marini Reboot is a 1 fl oz anti-aging serum centered around salmon-derived PDRN, peptides, ceramides, and hydration-supporting ingredients. At $160 per ounce, it is firmly positioned in the medical-grade skincare tier. Formulation & Ingredient Profile The formula combines: • PDRN (Polydeoxyribonucleotide) derived from salmon milt • Palmitoyl Pentapeptide-4 and additional peptides • Sodium hyaluronate for hydration • Ceramide NP and squalane for barrier support • Ferment lysates and botanical extracts for antioxidant and soothing support PDRN is often marketed for regenerative and repair-support benefits, particularly in post-procedure or compromised skin contexts. While topical PDRN data is more limited than injectable applications, the inclusion reflects a trend toward regenerative-focused skincare. The supporting ingredients are well selected and align with barrier reinforcement, hydration, and visible texture refinement. Texture & Application The serum has a lightweight, fast-absorbing consistency that layers well under moisturizers and SPF. It does not leave a heavy or occlusive residue. It integrates easily into both morning and evening routines. Performance With consistent use, skin appears more hydrated and smoother in surface texture. The barrier-supporting ingredients help reduce the appearance of dryness-related fine lines. It performs best as part of a structured routine rather than as a standalone solution. This is not an overnight transformation product. Improvements are incremental and align with cumulative use. Skin Type Compatibility Best suited for normal to dry or post-procedure skin seeking added resilience and hydration support. Sensitive users should patch test due to the complex ingredient profile. Value Consideration At $160 per ounce, the cost is significant. The ingredient deck is sophisticated, and the brand positions this within a regenerative, longevity-focused framework. Whether the price is justified depends on how much value you place on PDRN-based formulations and premium peptide systems. Comparable serums without PDRN exist at lower price points, but few combine this exact ingredient profile. Pros • Advanced ingredient formulation centered on PDRN • Strong hydration and barrier support components • Lightweight, layers well • Cruelty free and made in the USA Cons • High price per ounce • Long-term benefits require consistent use • Clinical data for topical PDRN is still emerging Bottom Line Marini Reboot is a high-end regenerative-style serum designed to support smoother, more resilient-looking skin over time. It integrates well into a comprehensive anti-aging regimen and features a thoughtful ingredient list. The primary barrier is cost. For those comfortable in the premium skincare category, it delivers a well-formulated option focused on recovery, hydration, and structural support. Read more

★★★★☆

Seems to help so far, but I wish it were fragrance-free

CustomerMarch 11, 2026

I was excited to try this premium face serum because I have heard such great things about the Marini brand and I've had good results from PDRN serums in the past. They tend to be my favorite serums, even though the others I've tried so far have been quite inexpensive. You can feel the quality of this product just by the container alone. The serum itself is silky and lightweight, and absorbs quickly. I have sensitive skin and have not had any negative reactions from this serum. My skin is quite damaged from exposure to sun and stress, and I believe the other PDRN serums I've used have had some positive effect. I'm hopeful that this product will continue to produce positive results, though I know I need to be patient and consistent. My only complaint is the scent. While it is pleasant and not too strong, even pleasant fragrances tend to irritate my sensitive eyes and sinuses. I find that layering a fragrance-free cream over it tends to help some. But I would prefer a fragrance-free product. It's no secret that this is an expensive skincare product and there are much cheaper options. This is out of my budget for skincare, but if after using it I determine this product has made a significant difference in my damaged skin, I will try to find a way to continue to purchase it. Read more

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