Desitin

Desitin Daily Defense Baby Cream with Zinc Oxide to Treat Relieve Prevent Diaper Rash Hypoallergenic Dye Phthalate Paraben-Free

127+ bought in the past month

$5.98$39.99

About this item

  • 4-ounce tube of Desitin Daily Defense Diaper Rash Cream works from the first use to help soothe, treat and prevent diaper rash
  • From the #1 choice for diaper rash relief by Pediatricians and parents, this infant diaper cream instantly forms a protective layer on your baby's skin for diaper rash relief and prevention
  • Made with zinc oxide, its fast-acting hypoallergenic formula helps seal out wetness to treat diaper rash from the first signs and is clinically shown to provide diaper rash relief
  • This diaper cream is specially formulated for babies' tender skin and is paraben-, phthalate- and dye-free so it's gentle enough to use at every diaper change
  • Its creamy formula goes on smoothly and wipes off easily, making Desitin Daily Defense Diaper Rash Cream your trusted partner for treating diaper rash from the first signs
$5.98
Was $39.99Save $34.01

Currently unavailable


Currently unavailable

Secure Checkout
Free Returns
30-Day Guarantee
Secure checkoutAll transactions are SSL-encrypted. Your payment info is never stored.
Free returnsReturn or replace within 30 days
Fast deliveryOrders ship within 1 business day and arrive in 4–8 days.
Buyer protectionIf your order arrives damaged or doesn't show up, we'll make it right.
24/7 supportOur team is here to help. Reach us anytime by email or chat.
Ships fromOur Warehouse
Returns
Easy Returns30-day return window
PaymentsSecure transaction

Product details

BrandDesitin
Item FormCream
Item Weight4 Ounces
Age Range (Description)Adult
Item Volume0.01 Liters

Technical specifications

is_discontinued_by_manufacturerNo
product_dimensions1.8 x 2.4 x 6 inches; 4 ounces
manufacturer_recommended_age1 month and up
item_model_number301
date_first_availableJune 19, 2017
manufacturerPfizer Consumer Health - J&J
best_sellers_rank#187,127 in Health & Household ( See Top 100 in Health & Household ) #261 in Diaper Creams #5,364 in Sales & Deals

From the brand

Product detailProduct detailProduct detail

Product videos

Product video 1

Customer reviews

4.85,635 ratings

Customers say

Customers find this diaper cream effective at treating and preventing diaper rash, with one noting it works even on adult skin.

★★★★★

So soothing and keeps skin dry.

NikkiMarch 15, 2016

This stuff is awesome! I have a sister with disabilities who is in a wheelchair and wears diapers, so my mom has been using this for years! I have actually tried it myself when I get irritation from sanitary napkins and this stuff is amazing. I don't really understand how it works, but it makes the area feel dry as if you'd used baby powder, but it is easier to apply and thicker so it protects the skin more. I honestly wish I had tried this for myself years ago! I would definitely trust this on a baby and would use this over baby powder to make them feel more comfortable. Read more

★★★★★

Muy recomendable

Mailen HernándezJanuary 8, 2026

Muy bueno muy recomendado siempre lo utilizo en casa me encanta Read more

Review image 1
★★★★★

Excellent product!

David Jesús Pajón EspinaApril 25, 2022

Excellent product! I've been using it for my daughter for relief of rash small skin injuries due to diapers or tight clothes rubbing, for almost 4 years since she was a baby. In 12h or 24h, work done. I've tried other brands but have to say this one has been the most effective. Also the product lasts a lot as you only need to apply a small amount. Read more

★★★★★

Use this daily

StephaniMarch 19, 2024

The best cream!! Use it daily to prevent diaper rash and so far we haven’t had any! Read more

★★★★★

Great for curing baby rash!

A&PJune 14, 2020

My 15 year old son did not have a big problem with baby rash until after he started teething. It got bad one day and it was really red and there was even some blood (dry skin). We asked our pediatrician what we should do and he recommended using Desitin. It got cleared up withing 6 days and even after a day you could see it was working! He is teething every couple of weeks now so occasionally he gets a rash (not as bad as the first time); so the first sign of a rash we use this so the rash goes away within a few days. If your little one is getting baby rashes, then I would definitely recommend this! Read more

★★★★★

Útil

Yaima Amayuela NápolesMay 20, 2025

La mejor crema para bebé. Siempre la he usado y lo ha protegido sobre quemaduras cuando usa su pañal además que sirve para cualquier tipo de quemaduras Read more

★★★★☆

Works Fast and Protects My Baby’s Skin All Day

Tanya’s FindsDecember 10, 2025

Desitin Daily Defense has become a must-have in my baby’s diaper bag. I bought it after trying a couple of other creams that didn’t help much, and I’m so glad I switched. The texture is smooth and easy to spread, and it creates a protective layer instantly without feeling too thick or sticky. Whenever my baby starts to get a little redness, I apply a thin layer during the next diaper change and the irritation is usually gone by the following change. It really does soothe and protect fast. I also love that it’s gentle enough for daily use and doesn’t cause any sensitivity issues. This cream gives me peace of mind because I know it prevents diaper rash before it even starts. Highly recommend it for any parent who wants something effective and reliable. Read more

Review image 1Review image 2Review image 3
★★★★★

Muy buena

belkyssApril 23, 2025

Me gusta la rapidez que la piel dañada se arregla. Siempre tengo en casa Read more

Recently Viewed