Dr. Sheffield's

Dr Sheffields Anti-Itch Cream with Histamine Blocker - 1 25 Oz 4

795+ bought in the past month

$9.97$12.99

About this item

  • INCLUDES: 1.25 ounce per tube of Dr. Sheffield's Extra Strength Anti-Itch Cream
  • CONTAINS: Diphenhydramine HCl 2%, topical analgesic; Zinc acetate 0.1%, skin protectant
  • FAST-RELIEF: From pain and itching associated with bites, minor burns, sunburn, minor skin irritations, and rashes
  • DRIES: Oozing and weeping of poison ivy, oak, and sumac
  • Made in the USA
$9.97
Was $12.99Save $3.02

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Product details

BrandDr. Sheffield's
Item Weight0.46 Pounds
Item dimensions L x W x H8.46 x 5.83 x 1.34 inches
Product BenefitsItch Control
Specific Uses For ProductInsect Bites Relief

Technical specifications

is_discontinued_by_manufacturerNo
product_dimensions8.46 x 5.83 x 1.34 inches; 7.36 ounces
date_first_availableDecember 23, 2016
manufacturerDr. Sheffield
best_sellers_rank#25,436 in Grocery & Gourmet Food ( See Top 100 in Grocery & Gourmet Food ) #1,324 in Dairy, Eggs & Plant-Based Alternatives

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Customer reviews

4.61,113 ratings

Customers say

Customers find the anti-itch cream works within seconds and is effective for bug bites, with one customer noting its success with eczema-prone skin.

★★★★★

Works well

David FinleyNovember 12, 2025

Great product! Read more

★★★★★

Super effective for environmental reactions in eczema-prone skin

SoCalDogfatherMay 5, 2022

Like many people, I suffer from mostly mild forms of what my physician calls "chronic dermatitis." For me, it's around the hands and oddly, the outer ear canals. The condition also resembles eczema in its itchy, flaky redness and tends to be aggravated by certain environmental factors like heat, sweat and so on. In my ears, I have often woke up to an irresistible urge to scratch, swab, anything to get rid of the damned itch! After trying countless remedies, I found this stuff - simply a skin protectant with an antihistamine - the two and only tools I needed to get my condition under control. One application each and every morning and I can tell you I'm feeling at least 80% better throughout the day. A second application ups that relief even more. Since using this cream (very sparingly at that), I have felt consistent relief and a steep reduction in inflammation. This stuff is mild, fragrance-free and at this price, an absolute no-brainer for anyone seeking relief from dry, itchy patches of skin. Read more

★★★★☆

Dr. Sheffield anti itch cream

Delores HelmsDecember 26, 2025

This is a great creme. It was delivered in a few days. Very pleased. Read more

★★★★★

Great value and relieves the most intense itching

Lisa ZFebruary 26, 2023

What's not to like? The price beats anything you can find at the drugstore and it works! It relieves what I call "stabbing itching" as well as regular constant itching and doesn't irritate my skin. I also found that when the tube appears to be empty, cut off the flat end with scissors and there is still quite a bit left inside that you can use. It is a cream and does not have any perfumes added to it. Great stuff! Read more

★★★★★

This stuff works great

CustomerDecember 3, 2019

This stuff is awesome.... I started using it about a year ago when nothing else really worked on my ears. I have psoriasis in my outer and inner ear and sometimes it just starts itching non stop. Wth my medical benefits I get free over the counter pharmacy supplies and I saw this and I ordered it back then and it stopped the itching when nothing else would. And recently I started having to see a lymphedema specialist to get my legs wrapped in compression bandages and I just couldn't tolerate them because my legs started just started itching underneath the bandaging like crazy and I would have to take them off because I just could not stand the maddening itching. I remembered I had this anti itch cream. I took it in with me to my appointment and ask the therapist to put that on before she put on the layers of compression bandaging what a difference no itching whatsoever all day and all night as I have to wear them 24 hrs till my next appointment for maximal benifit. Read more

★★★★★

I live deep in the country down south....anti-itch creme is a necessity...and this is it!!

ChrystelMay 17, 2020

I am constantly working outside, clearing brush and landscaping our huge yard. Which translates to me getting bitten by every stinging insect that resides in my yard. Or me rubbing up against some irritating plant that sets my skin on fire. Someone in my family needs anti-itch cream at least once a week....sometimes everyday. This stuff works just as well, if not better than the more recognizable name brands and is far more economical. I am going to order more. If you plan on being outside a lot, stock up on this stuff. It is sooooo worth the money. It works fast, absorbs very well, and it doesn't leave a film on your skin or smell weird. I highly recommend it. Read more

★★★★★

Favorite Anti-Itch Cream

R ShultzFebruary 11, 2025

This is my favorite anti-itch cream - a little goes a long way - very effective! Read more

★★★☆☆

Might not be the original formula

M. GordonJune 5, 2020

I broke out in hives. After the hives had visibly gone, I still had itching. My grandfather brought the product from a local store and raves about it. I did not have the same option. Weeks after I gave him a tube and he said it’s not the original formula. Read more

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