Neutrogena

Neutrogena On-The-Spot Acne Spot Treatment Cream with 2 5 Benzoyl Peroxide Gentle Face Blemish Medicine for Acne-Prone Skin

1390+ bought in the past month

$8.97$10.84

About this item

  • Acne spot treatment: Targets pimples with gentle 2.5% benzoyl peroxide; Effectively treats breakouts without over-drying or irritating skin, making it ideal for daily use on acne-prone and dry skin types
  • Vanishing cream formula: Lightweight, fast-absorbing, and invisible on skin; This acne treatment for face delivers lasting results and can be used up to three times daily for clearer, healthier-looking skin
  • Clinically proven results: Clears skin starting day 1 without stinging or burning; Dermatologist-tested formula goes deep down into pores to kill the acne bacteria that can cause pimples
  • Gentle for dry and acne-prone skin: Perfect for those seeking effective acne care without over dry-ing or discomfort
  • Neutrogena On-The-Spot Acne Spot Treatment cream is an effective acne treatment for face in a convenient 0.75 oz tube
$8.97
Was $10.84Save $1.87

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Product details

Item FormCream
ScentUnscented
BrandNeutrogena
Product BenefitsHydrating
Skin TypeDry

Technical specifications

is_discontinued_by_manufacturerYes
product_dimensions1.45 x 3.95 x 3.95 inches; 0.75 ounces
item_model_number2620649002
upc070501017906
manufacturerKenvue
best_sellers_rank#1,337 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #41 in Facial Serums

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Customer reviews

4.63,818 ratings

Customers say

Customers find the acne spot treatment effective, with one noting it shows results within one treatment. Customers consider it good value and appreciate its quick-drying properties.

★★★★★

LADIES OVER 40!!!!!! This works for Hormonal acne

Kelly AdamsJanuary 8, 2026

5 Stars!!!!! Excellent product for those over 40 whose face decides that hormonal acne is fun. I have been fighting acne on my chin for months..i got desperate and smart....this cleared it up in 3 days. My skin is back to normal and no more painful, icky redness and bumps. Make sure that you use a moisturizer to help with the drying process. I applied at night before bed and then before I put on makeup. Read more

★★★★★

Highly recommend effective, gentle, and affordable!

nNovember 7, 2025

⭐️⭐️⭐️⭐️⭐️ Actually Works Fast and Gentle! I’ve tried so many acne spot treatments, but the Neutrogena On-The-Spot Acne Treatment Gel is one of the few that actually works without completely drying out my skin. The 2.5% benzoyl peroxide strength is strong enough to reduce pimples quickly but still gentle enough for sensitive skin. I use a small amount at night on breakouts, and by the next morning, the redness and size are noticeably smaller. It absorbs fast, doesn’t sting, and layers well under moisturizer or makeup. A little goes a long way, so the tube lasts a while. If you’re looking for a reliable spot treatment that clears pimples without irritation, this is it. Highly recommend effective, gentle, and affordable! Read more

★★★★★

A Dermatologist-Approved Miracle Worker for Stubborn Breakouts!

Sean KewalramaniJuly 23, 2025

★★★★★ A Dermatologist-Approved Miracle Worker for Stubborn Breakouts! After a decade-long battle with acne, I can confidently say Neutrogena's On-The-Spot Acne Treatment is one of the most effective over-the-counter solutions I've ever used. This 2.5% benzoyl peroxide formula delivers professional-level results without the harsh side effects of stronger prescriptions. Why This Spot Treatment Stands Out: ✔ Clinically Proven Efficacy - Visible reduction in redness and swelling within just 8 hours of application ✔ Gentle Yet Powerful Formula - The 2.5% benzoyl peroxide concentration is strong enough to combat acne bacteria while being gentle on sensitive skin ✔ Vanishing Technology - Leaves no white residue or chalky finish (unlike most BP treatments) ✔ Precision Application - The slim tube allows for targeted treatment without wasting product ✔ Dermatologist Recommended - Backed by decades of Neutrogena's skincare science Real Results I've Observed: Overnight Transformation: 90% reduction in pimple size by morning Preventative Power: Regular use prevents new breakouts from forming Skin-Friendly: No excessive dryness or peeling when used as directed Pro Tips for Best Results: Apply a thin layer to clean, dry skin before bed Follow with oil-free moisturizer if prone to dryness Use at first sign of breakout for maximum effectiveness Final Verdict: This tiny but mighty tube has earned a permanent place in my medicine cabinet. It outperforms more expensive alternatives and delivers consistent results without irritation. For anyone struggling with occasional breakouts or persistent acne, this is hands-down the most reliable spot treatment available without a prescription. Worth every penny - my skin's emergency responder! Read more

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★★★★★

Haven’t had a pimple sense

BriannaDecember 30, 2025

Works so amazing! I apply in the morning all over face and at night! I wish I had 1,000 of these! Read more

★★★★☆

Neutrogena has great products .

ANN DJune 3, 2025

Neutrogena has great products. I use it for my face and it helps contour my psoriasis. Read more

★★★★★

it really works!

Dianne K.December 13, 2025

I think this product actually works. I recently had so many tiny pimples break out on and around my nose and chin. Don't know why as this was unusual. So i got this and just put a dot of it everywhere i saw one and within a couple of weeks, they were gone. So this had to be the reason. Easy to apply. Good price. I still have plenty left. Read more

★★★★★

A tiny dab will do and you won't regret it!

EricaOctober 7, 2025

We all know our skin changes as we do through the years. I didn't develop acne until my 30's and have struggled to find the right treatments. This works effectively and quickly. Don't use too much as it can really dry out your skin. A tiny dab will do! Read more

★★★★★

Good helper to clear pimples

MercedesDecember 23, 2025

Love this stuff for deeper pimples. Might take more than one application if it’s a big one but extremely helpful. A little goes a long way. Read more

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