Similac

Similac 360 Total Care Infant Formula Has 5 HMO Prebiotics Our Closest Prebiotic Blend to Breast Milk Non-GMO

423+ bought in the past month

$39.88

About this item

  • CLOSER TO BREAST MILK THAN EVER BEFORE: Similac 360 Total Care, our biggest formula breakthrough, has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk
  • 360 WHOLE-BABY SUPPORT: Nutrition designed for immune support, brain development, and digestive health
  • HELPS STRENGTHEN THE IMMUNE SYSTEM: Similac 360 Total Care is designed to help strengthen baby’s immune system
  • CONVENIENT & READY TO USE: Great for on-the-go and late-night feeding; no mixing required
  • TRUSTED BRAND: Similac is the #1 infant formula brand chosen by parents
$39.88

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Product details

BrandSimilac
Size2 Fl Oz (Pack of 48)
Item Weight10.1 Pounds
Allergen InformationGluten Free
Item FormReady-to-Feed

Technical specifications

product_dimensions1.76 x 1.76 x 4.31 inches; 10.1 Pounds
date_first_availableAugust 31, 2021
manufacturerAbbott Laboratories
best_sellers_rank#29 in Baby ( See Top 100 in Baby ) #1 in Liquid Baby Formula

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Customer reviews

4.77,630 ratings

Customers say

Customers find this formula to be high-quality and convenient, particularly appreciating its ready-to-feed format and travel-friendly bottles.

★★★★★

Used this Brand for Both Our Children, and it Hasn't Disappointed Yet, Great Value, Great Product!

Collin M.October 27, 2025

These ready-to-feed bottles have been fantastic for both our newborns. We used the same brand with her older sister, and it’s been consistently reliable both times. It’s actually the same formula the hospital provided us with, and it continues to work wonderfully. We’re using it to supplement natural feeding to help with weight gain, and it’s been very effective, our baby is gaining steadily, with minimal spit-up as long as we pace her feedings. The formula flows nicely, seems very gentle on her stomach, and gives us confidence that she’s getting good nutrition. The bottles also have clear measurement markers on the side, which makes tracking very easy. The price is very reasonable for the convenience and quality. All in all, it's a trusted brand that continues to deliver, and highly recommended! Read more

★★★★★

Great value, great product

Joly DebDecember 26, 2025

Very satisfied after using this formula, easy to feed and convenient for going out. Ready to feed and great quality. Read more

★★★★★

Great gift for a new mom

LyndseyJanuary 14, 2026

Purchased for a friend who had just came home with a newborn. Being able to have this delivered to her home and have the ease of access to a ready made bottle was nice to be able to give. Highly recommend doing this for your new mom friends who use formula. Read more

★★★★★

Highly recommended!

ChristopherAugust 3, 2025

We started using Similac 360 Total Care Advance when we were supplementing with formula, and it’s been a lifesaver. Our baby took to it right away — no issues with gas, fussiness, or spit-up like we experienced with a couple of other brands. It’s gentle on the tummy and seems to digest really well. What gave us confidence is knowing it has a blend of five HMO prebiotics, designed to help support baby’s immune system — similar to what’s found in breast milk. Plus, it doesn’t have palm olein oil, which is something we were trying to avoid. Mixes smoothly, doesn’t clump, and the powder doesn’t have a strong or unpleasant smell. Our little one has been growing well, happy, and content — and as parents, that’s all we can ask for. Definitely recommend Similac 360 Total Care Advance to anyone looking for a high-quality, well-balanced formula that’s easy on a baby’s system. Read more

★★★★★

Good formula

MadiDecember 12, 2025

Literally saved my baby. We had a significant tongue tie early on and were losing weight. The hospital provided this formula and there was almost instant improvement Read more

★★★★★

“Convenient, Gentle, and Closest to Breast Milk—A Lifesaver for Busy Parents”

saitejaAugust 8, 2025

I’ve been using the Similac 360 Total Care Ready-to-Feed 2 oz bottles (48-pack) and couldn't be more impressed. From the start, my baby took to it wonderfully—no fussing, gas, or digestive discomfort. The bottles are utterly convenient, especially during nighttime or on-the-go feedings; there's no mixing—just open and serve—making those bleary-eyed middle-of-the-night sessions so much smoother. What really stands out is the nutritional formulation. It features an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk, offering immune support, digestive health, and overall developmental benefits . Plus, it’s non-GMO and contains no artificial growth hormones, bringing extra peace of mind Pros: Extremely convenient, gentle on digestion, closely mimics breast milk, immune and brain support via 5 HMO prebiotics, non-GMO, no artificial growth hormones. Cons: Higher cost per ounce compared to powder. Read more

★★★★★

Good deal!

NickDecember 8, 2025

Time saver at begging and also convenient for traveling but if baby gets bigger will need more than just 1 bottle Read more

★★★★☆

Love, But There’s a Purchase Limit

AlexaJanuary 3, 2026

We’ve used this for my now 3mo since she’s been born. The hospital gave it to us & we never switched. (Actually we did try another brand of powder formula because we thought this was causing her gas, but it wasn’t) While it is more expensive than the powder (thankfully my family helps us out with the formula cost), I do think it’s worth it. My baby was super gassy in her first 2 months, but I don’t think it had anything to do with the formula. The ready-to-feed is so convenient. The only reason it gets 4 stars instead of 5 is because 1.) it goes bad fast. Once you pour it into the bottle, you technically only have an hour to use it before you have to dump it (you can stretch it to 2 hours but that’s it.) 2.) There’s a purchase limit. You can only buy 4 cases a week, which I think is ridiculous. My baby is drinking more now that she’s older, & while I understand I can use the 8oz bottles, you risk wasting more of the formula (which is expensive to begin with) because the time limit is still the same. I wish I could buy more than 4 a week. Read more

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