If you're debating on trying this..
I just saw my dentist today, both he and his assistant praised me for how clean kept my teeth are. I brush morning and night with this SP-6 toothpaste and I floss at night (brush, floss, brush, rinse). I dont think I'll ever use another toothpaste after all the research I've done and how well it works, plus I love the minty flavor. Now for the research: 1. Lactobacillus paracasei ADP-1 is a postbiotic, or a deactivated form of the probiotic bacteria Lactobacillus paracasei, found in products like USANA Oral Care Whitening Toothpaste. It provides oral health benefits, such as helping to maintain a clean mouth and promoting a healthy bacterial balance. The ADP-1 strain has demonstrated an ability to provide an exceptional clean and support overall oral wellness by delivering the benefits of the probiotic L. paracasei in a stable form. 2. The Ligilactobacillus salivarius species is commonly found in the oropharyngeal-gastrointestinal tract and has shown strong antimicrobial properties against harmful dental pathogens. Specifically, it has the potential to inhibit the growth of bacteria that cause cavities and gum disease. University of Michigan trials showed that users of a toothpaste containing L. salivarius saw a 34% decrease in plaque accumulation over eight weeks. 3. While Lacticaseibacillus paracasei is a well-researched probiotic for oral health, there is no evidence of a commercially available toothpaste containing the specific strain ET-66. The ET-66 strain has been studied in a laboratory setting for its ability to inhibit oral pathogens, but other strains of L. paracasei are the ones found in commercially produced probiotic toothpastes. A 2020 study investigated the ability of several heat-killed lactic acid bacteria to inhibit four distinct oral pathogens. The results showed that heat-killed L. paracasei ET-66, along with AP-32 and CT-53, had the highest overall pathogen inhibition scores. 4. Lactobacillus plantarum strain LPL28 is being explored for its beneficial effects on oral health, including its potential use in toothpastes and other oral hygiene products. It has been shown to effectively inhibit harmful oral pathogens, such as Aggregatibacter actinomycetemcomitans and Helicobacter pylori, and regulate the oral microbiome. Research is ongoing to establish its efficacy and safety for preventing dental caries, gum disease, and improving oral immunity through modulating salivary IgA levels. By introducing beneficial bacteria, LPL28 helps to restore balance in the oral microbiome, which can be disrupted by pathogens. Some studies suggest that LPL28, or postbiotics derived from it, can increase the concentration of salivary Immunoglobulin A (IgA), a key component of the body's oral immune response. 5. L. rhamnosus can inhibit the growth of cariogenic (cavity-causing) bacteria, such as Streptococcus mutans, by producing antimicrobial substances. Studies in children have shown that introducing L. rhamnosus can lead to fewer cavities over time. For periodontal diseases and gingivitis, L. rhamnosus can reduce harmful pathogens like Porphyromonas gingivalis. Its mechanisms include competing for adhesion sites on oral surfaces and modulating the body's immune response to fight infections. L. rhamnosus is resistant to acidic environments and can effectively colonize the oral cavity, which helps it remain effective. 6. Studies show that the probiotic strain Lacticaseibacillus paracasei LC86 and other L. paracasei variants have potential oral health benefits when used in toothpaste. The mechanism involves restoring the oral microbiome by competing with harmful bacteria, although efficacy can vary by strain and product. A 2025 clinical trial using toothpaste with L. paracasei in orthodontic patients found a significant improvement in gingival bleeding, an indicator of inflammation. Other research with a different L. paracasei strain also showed potential for managing mild to moderate gingivitis. The benefits are highly dependent on the specific strain used in the product. For instance, L. paracasei LC86 has been primarily studied for its impact on gut microbiota, cognitive function, and bone health in animal models, not specifically for oral applications. Its effect in toothpaste would be based on the general benefits of L. paracasei. In Conclusion: While traditional toothpastes often use harsh chemicals to kill all bacteria, probiotic toothpastes help establish a healthier balance of microorganisms in the mouth. 7.5% Hydroxyapatite toothpaste uses a natural mineral, the same mineral that makes up tooth enamel, to strengthen and repair teeth by filling microscopic cracks and smoothing the tooth surface. This fluoride-free alternative helps reduce sensitivity by restoring enamel and can also decrease surface stains, leading to a naturally whiter smile. How it works: • Mimics Tooth Structure: Hydroxyapatite is the main mineral component of natural tooth enamel and dentin, providing a natural way for the toothpaste to interact with your teeth. • Remineralization: It deposits calcium and phosphate ions directly onto the tooth surface, helping to rebuild and strengthen the enamel, which is the body's hardest substance but does not naturally regenerate. • Repairs Damage: By integrating into the enamel, it fills tiny cracks and smooths out microscopic roughness, making the enamel stronger and more resistant to acid erosion. Benefits: • Enamel Strengthening: It actively helps restore the natural structure of the teeth. • Sensitivity Reduction: By repairing enamel and restoring its smooth surface, it can block stimuli that cause sensitivity to hot, cold, or sweet foods and drinks. • Stain Removal: The smoothing effect on enamel makes it harder for plaque and stains to adhere, which contributes to a brighter, whiter smile. • Fluoride-Free Option: It serves as a natural alternative to fluoride for enamel protection. • Supports Oral Health: Promotes overall oral balance and can help prevent issues like gingivitis. Safety and Usage: • Concentration: International agencies consider up to 10% hydroxyapatite safe for fluoride-free toothpaste. Read more













