Systane

Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count

130+ bought in the past month

$21.00$29.99

About this item

  • Triple-Action Dry Eye Relief: Systane Pro Preservative Free Eye Drops hydrate, restore and protect dry eyes for up to 12 hours of relief
  • Long-Lasting Hydration: Systane Pro Preservative Free lubricating eye drops are formulated to support extended hydration for all types of dry eye relief
  • Tear Evaporation Protection: This unique formula helps lock in moisture and reduce tear evaporation
  • Preservative-Free Formula: The gentle, preservative-free formula is ideal for sensitive eyes
  • Trusted Brand: Systane is a trusted name in eye care, recommended by eye care professionals for its effective and reliable relief
  • Convenient Size: The 10mL bottle is perfect for daily use, offering you triple action dry eye relief at your fingertips
  • Contact Lens Friendly*: safe for use with soft contact lenses
$21.00
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Product details

BrandSystane
Item Weight0.68 Ounces
Item dimensions L x W x H1.25 x 2.56 x 4.25 inches
Product BenefitsEye Care
Specific Uses For ProductDry Eye

Technical specifications

product_dimensions1.25 x 2.56 x 4.25 inches; 0.68 ounces
date_first_availableFebruary 1, 2025
manufacturerAlcon Laboratories
best_sellers_rank#1,658 in Health & Household ( See Top 100 in Health & Household ) #7 in Dry Eye Relief Products #44 in Vision Products

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Customer reviews

4.51,448 ratings

Customers say

Customers find these eye drops effective for dry eyes, providing immediate relief and keeping them moist longer than regular drops.

★★★★★

Effective Relief for Dry Eyes, but Expect Brief Blurriness After Use

Stanley A OhisJanuary 6, 2026

I spend long hours in front of screens and started dealing with frequent dry, irritated eyes. This Systane product came in highly recommended for something strong enough to actually relieve discomfort, but gentle enough for regular use without preservatives. Been using these drops consistently for over a year now, usually once or twice a day, especially after long work sessions. The soothing effect is noticeable almost immediately. Within seconds, my eyes feel more comfortable and less strained, which makes it easier to keep working or reading. They feel effective without causing stinging or irritation, and I haven’t had any negative skin reactions around the eyes, even with frequent use. For me, right after applying the drops, my vision gets slightly blurry for the first few minutes. It clears up on its own, but it’s something to plan around, especially if you need to look at a screen or drive right away. Another minor issue is the bottle design. Some bottles don’t open smoothly, and when squeezing, it’s easy to dispense more drops than intended. That can be wasteful, especially for a product that isn’t cheap. These feel more substantial than basic artificial tears. They don’t just coat the eye briefly; the relief lasts a reasonable amount of time. Because of the preservative-free formula, I feel comfortable using them regularly, which helps justify the price, though I do wish the value for money were slightly better given the packaging issues. Read more

★★★★★

Most soothing and hydrating eyedrops on the market

Chad BenedictJanuary 4, 2026

I recently had lasik eye correction and these drops are so soothing. In my opion they are better than the competitors. The hydration is long lasting and effective. I tried a few different brands but the effects do not last like these. The preservative free allows you to use them as needed and wont irritate your eyes. They do not leave your eyes feeling sticky and you can't beat the price. Read more

★★★★★

Good for dry eyes. See doctor if it doesn’t relieve consistent dry eyes a short period

lukaNovember 24, 2025

The Systane PRO PF Multi-dose Preservative-Free works really well if your eyes are dry. It does have a slightly milky mixture where it’s best if you use them without contact lenses. It will not damage the contacts, but just blurry for a little bit with the kind of lenses on. The substance in this is slightly sticky on the eyes, but it will wear off after a short time. I would try to use an exact drop so you don’t waste using it. I would recommend this product. Study the consistency of other Systane products so you know what the product is made of. Read more

★★★★☆

Great Product, But Bottle Design Leaves Much Room For Improvement

Sam and Nico’s NanaDecember 20, 2025

This product is more comfortable in my eyes than other brands I’ve used, and the moisturizing effects seem to last longer. So far I’ve experienced no rebound irritation at all. However the design of the dropper part of the bottle is awkward to use. It’s hard to position the opening directly over my eye, and I often just miss getting the drops into my eye. It’s also necessary to squeeze with more pressure and for a longer time to get the drops to come out of the bottle compared to other “usual” bottle designs. Bottom line: I love the medication, but am not a fan of the bottle design. Read more

★★★★★

very good eye drops

David BergJanuary 11, 2026

my eye doctor recommended these eye drops. Eye Doctor said these eye drops cost more but should help. Eye drops work very well and kept my eyes from drying out. I apply drops in morning and evening. I recommend these eye drops to my friends. Read more

★★★★★

THESE CAME I VERY HANDY AFTER A RECENT EYE SURGERY

EM DARBYSHIREDecember 18, 2025

MY SURGEON RECOMMENDED PRESERVATIVE-FREE DROPS, AND I LOVED THE LOW COST IN COMPARING OTHER BRANDS. THE DESIGN IS ALSO NOTABLE. I DIDN'T DEPEND ON DROPS PREVIOUSLY, BUT THIS PROVIDED NECESSARY RELIEF. THE BLUNT DESIGN OF THE BOTTLE HELPED ME APPLY THE DROPS TO MY EYES. i AM VERY APPREHENSIVE WHEN APPLYING THEM, BUT I FOUND IT EASY AFTER A LOT OF PRACTICE. I WAS UNFAMILIAR WITH THIS BRAND PREVIOUSLY, BUT AM VERY SATISFIED WITH THIS PRODUCT. Read more

★★★★★

Lubricate vey well.

Joel J JacksonJanuary 5, 2026

It lubricants dry eye very well. Greatly helps sleep. Wake up and eyes are not gritt Read more

★★★☆☆

Good Relief, But Pricey for What You Get

James SandovalNovember 13, 2025

I tried the Systane PRO PF Preservative-Free Eye Drops hoping for long-lasting comfort, and while they do provide solid relief from dryness and irritation, the effects don’t seem to last as long as I’d like. The drops feel smooth going in and don’t cause any burning, which is a big plus. I also appreciate the preservative-free formula—it’s gentle on sensitive eyes. However, the bottles are small, and for the price, I expected a bit more product or longer-lasting hydration. Overall, they work well, but the value could be better. Read more

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