Doctor's BEST

Doctors Best High Absorption Magnesium Glycinate Lysinate Supplement - 100 Chelated for Maximum Absorption - Magnesium for Sleep

1328+ bought in the past month

$19.79$29.00

About this item

  • 6X ABSORPTION: Magnesium glycinate is good, lysinate glycinate is even better. Fortified and carried by not one but two amino acids, our supplement takes the most direct route into your system, making for much faster absorption and no upset stomach.
  • MAGNESIUM GLYCINATE AND MORE: Beyond faster absorption, magnesium glycinate lysinate offers the added benefits of each amino. Glycine has been known to help support brain, sleep, and liver functions, while lysine may help support bones and muscles.
  • PROVEN INGREDIENTS: Our magnesium glycinate supplement is not buffered with fillers or additives and is vegan, non-GMO, gluten-free, and soy-free. We believe composition is everything, and every formula is doctor-approved.
  • SLEEP AND RELAXATION: Magnesium is crucial to overall wellness, and our supplement is specially formulated to aid with supporting healthy, restful sleep and relaxation by helping regulate melatonin, cortisol, and muscle function.
  • DOCTOR'S BEST: Better living begins with good nutrition, and good nutrition starts with sound science. For over 30 years, we have been dedicated to providing only thoroughly researched, rigorously tested, and clinically-approved supplements.
$19.79
Was $29.00Save $9.21

In Stock

DeliveryEstimated 3–5 business days · Final delivery speed and cost are confirmed at checkout
Easy Returns · 30-day window
This order is a gift

In Stock

Secure Checkout
Free Returns
30-Day Guarantee
Secure checkoutAll transactions are SSL-encrypted. Your payment info is never stored.
Free returnsReturn or replace within 30 days
Fast deliveryOrders ship within 1 business day and arrive in 4–8 days.
Buyer protectionIf your order arrives damaged or doesn't show up, we'll make it right.
24/7 supportOur team is here to help. Reach us anytime by email or chat.
Ships fromOur Warehouse
Returns
Easy Returns30-day return window
PaymentsSecure transaction
Currently unavailable
Easy Returns · 30-day window

Product details

BrandDoctor's BEST
Item FormTablet
Primary Supplement TypeMagnesium
Unit Count240 Count
FlavorUnflavored

Technical specifications

is_discontinued_by_manufacturerNo
product_dimensions3.13 x 3.13 x 5.19 inches; 0.89 ounces
item_model_numberDRB-00087
date_first_availableOctober 2, 2001
manufacturerDoctor’s Best, Inc
best_sellers_rank#288 in Health & Household ( See Top 100 in Health & Household ) #8 in Magnesium Mineral Supplements #47 in Sales & Deals

From the brand

Product detailProduct detailProduct detailProduct detailProduct detailProduct detailProduct detailProduct detailProduct detailProduct detailProduct detailProduct detail

Product videos

Product video 1

Customer reviews

4.574,114 ratings

Customers say

Customers find this magnesium supplement to be of good quality and effective, particularly for cramp relief and sleep quality, with many noting it helps with leg cramps and falls asleep faster.

★★★★★

Well-tolerated magnesium with noticeable benefits

NerkDecember 29, 2025

I’ve tried a few different magnesium supplements over the years, and this one has been the easiest for me to tolerate. The capsules are easy to take, and I appreciate that this is a chelated form, which is known for better absorption compared to some other types. After using it consistently, I noticed improvements in overall relaxation and muscle comfort, especially in the evenings. It didn’t upset my stomach, which has been an issue for me with other magnesium products in the past. This has become a regular part of my routine, and I’m very happy with the quality and consistency so far. If you’re looking for a high-quality magnesium supplement that’s gentle and effective, this one is worth considering. Read more

★★★★★

these pills are HUGE, but the benefits are even bigger.

lDecember 2, 2025

when i first opened this bottle my eyes bugged out because these pills are ginormous. i had no idea how i was going to swallow them, but they go down soooooo easy. there have been a couple times where i struggled to get them down using water, but if i used juice or a carbonated drink instead, it went down easy peasy. i've only been taking these for around 3-ish weeks but have noticed a significant difference in my levels of anxiety, as well as it helping my gut which is sluggish normally. i cannot recommend these enough and will continue to buy them as long as they are available. please do not ever reformulate these! these are perfect!!! Read more

★★★★★

FANTASTIC PRODUCT IN MANY WAYS (Stess, Anxiety, Insomnia)!!! Read on to benefit from my research.

ToddApril 13, 2017

Your reasons for coming across this product are probably varied. One thing you may have found frustrating was trying to determine which type of magnesium (atomic symbol for magnesium is Mg) is right for you (there are over 20 magnesium variations and I researched them all). From the very basic (Mg) hydroxide (often used in products to aid in clearing constipation...think Milk of Magnesia) to this finest form of (Mg), Magnesium Glycinate (Mg that has undergone a chelating process with another chemical compound, lysinate). So what does this mean to you? Magnesium glycinate is the most bioavailable form of (Mg) there is. By going through the chelating process this (Mg) has the smallest size molecular structure of all of the (Mg)s. It makes it's way into all of your tissues and most importantly IT CAN PASS THE BLOOD/BRAIN BARRIER. Not long after taking you will most likely notice a calming effect. Magnesium Glycinate has long been called the original supplemental "chill pill". It acts as a calmative on the entire nervous system. One person got ahold of me with the information that this product even helped with her IBS. Makes sense considering it's nerve calming effect. I was seeking out a product that would help with STRESS/ANXIETY during the day AND also act as an aid with my ONSET (difficulty falling asleep) INSOMNIA as well as my EARLY AWAKENING INSOMNIA. I found what I needed right here and so have my friends that have ordered and used the product after my success. Two tablets (400 mg total) is listed as 100% of the Recommended Daily Allowance. That is a minimal number. It can be well exceeded. That value does not take into account the fact that about 70% of the U.S. population is (Mg) deficient. I take one 200mg tab twice a day to help with stress/anxiety. If you are really bad off take 2. Would you like help in falling asleep and staying asleep? Take between 400 mg and 800 mg at bed time. You would of course start at 400 mg. I was successful with 400 mg for 3 days, then 600 for 3 days, the finally at 800 mg. If you have any concerns make the jumps 1 week apart. Magnesium has it's own way of letting you know if you have gone beyond your maximum threshold...you will get diarrhea. No long and protracted bout, but you will know (remember the Milk of Magnesia?). Perhaps go back to your pre-diarrhea level, or better yet slow down in the increase speed. The body will most likely adjust. Now, as to this product having any interactions with medications you may already be taking. Just Google a "medication and supplement interaction checker". For me I had one interaction and that was with my gabapentin. I must take my (Mg) two hours before taking my gabapentin or the proper absorption or the gabapentin could be stunted. This is the most common medication interaction with (Mg). Don't want that. In summary I find this product to be a VERY effective tool in dealing with stress, anxiety, and insomnia! What could be better? Good Luck, Todd ***UPDATE*** I was disappointed that I could not take this magnesium at bedtime due to my taking of gabapentin. There is most definitely a "golden hour" of relaxation with this product. I contacted my physician regarding the gabapentin/ magnesium glycinate issue. There is NO requirement to separate this product from your gabapentin. The interaction I found was with more elemental forms of (Mg). I now take at bedtime and fall asleep faster and with a more serene feeling. I apologize for the incorrect information. Read more

★★★★☆

Horse pills

SuDecember 16, 2025

I hate that these are GIANT pills, I found them ridiculously hard to swallow. However, they are effective and high quality. Read more

★★★★★

Gentle on the Stomach and Truly Effective

Rich ReviewsSeptember 25, 2025

Gentle on the Stomach and Truly Effective I’ve tried several forms of magnesium over the years, and this Doctor’s Best High Absorption Magnesium Glycinate Lysinate is one of the few that consistently delivers results without the stomach upset some other types can cause. The tablets are small enough to swallow easily, and I like that each serving provides 200 mg of elemental magnesium that’s chelated for better absorption. After a couple of weeks of steady use, I noticed more restful sleep and fewer nighttime muscle cramps—something that had been bothering me after workouts. Unlike magnesium oxide or citrate, this doesn’t send me running to the bathroom, which makes it much more practical for daily use. The bottle size is generous (240 tablets), so it lasts a good while, even with regular use. Things to keep in mind: the tablets are a bit chalky if you let them sit on your tongue too long, so swallowing quickly with water is best. Also, while two tablets is a serving, people with higher needs may want to discuss dosage adjustments with their doctor. Bottom line: A well-absorbed, stomach-friendly magnesium that supports sleep, relaxation, and muscle health—an excellent choice for long-term supplementation. Read more

Recently Viewed